Monkey ICOS-hIgG4-B7/CD28 Family-Cambridge Bio

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Monkey ICOS-hIgG4

Cat No.:    03-04-0076
Product Name:    Monkey ICOS-hIgG4
Size:    50 μg
Price:    ￥2400

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Cat No.: 03-04-0076
Product Name: Monkey ICOS-hIgG4
Description: CD278 or ICOS (Inducible T-cell COStimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells, which nhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes
Type: Protein
Property: Protein
Source: HEK293
Genbank No.: NP_001253918 ( aa.20-141)
Applications: WB,ELISA,Immunogen
Formulation: Each vial contains 50μg purified protein(1mg/ml) in PBS(pH7.4).
Purity: >95%
Storage: Store at -80°C,Avoid freeze / thaw cycle.
Limitation: For research use only,not for use in diagnostic procedures.